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ActHIB Drug Interactions

Warfarin, azathioprine, and prednisone are among the medications that can cause drug interactions with ActHIB. Such reactions can cause the vaccine to be less effective and may increase the risk of side effects. To guard against these and other problems, tell the healthcare provider giving the ActHIB injection about all medicines your child is taking, including vitamins and supplements.

An Overview of Interactions With ActHIB

ActHIB® (Hib vaccine) can potentially react with a few medications. Some of the medicines that may lead to ActHIB drug interactions include:
    • Chemotherapy (as well as radiation treatment)
    • Corticosteroids, such as:
      • Betamethasone (Celestone®)
      • Cortisone
      • Dexamethasone (Decadron®)
      • Fludrocortisone (Florinef®)
      • Hydrocortisone (Cortef®)
      • Methylprednisolone (Depo-Medrol®, Medrol®)
      • Prednisolone (Pediapred®)
      • Prednisone
      • Triamcinolone (Kenalog®)
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ActHIB Vaccine Information

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