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ActHIB Side Effects

Potentially serious, even life-threatening, side effects of ActHIB include unexplained swelling, wheezing, or seizures. Such side effects should be reported to a healthcare provider right away. Fortunately, such problems are rare, and most children experience mild reactions to the vaccine (if any), such as redness or tenderness at the injection site and irritability.

An Introduction to ActHIB Side Effects

As with all vaccines, side effects are possible with ActHIB® (Hib vaccine). However, not everyone who receives the vaccine will have problems. In fact, most children tolerate it quite well. If adverse reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with ActHIB. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of ActHIB

ActHIB has been studied thoroughly in clinical trials, and possible side effects were carefully documented. In these studies, the most common reactions to ActHIB included:
  • Pain, redness, and swelling at the injection site
  • Fever
  • Irritability
  • Lethargy.
The exact percentages of these side effects were not reported.
ActHIB can be mixed with Tripedia®, a DTaP (diphtheria, tetanus, and pertussis) vaccine. In studies, common side effects of this combination included:
  • Irritability -- in up to 27.3 percent of children
  • Drowsiness -- up to 36.4 percent
  • Tenderness at the injection site -- up to 20 percent
  • Loss of appetite -- up to 12.7 percent
  • A lump at the injection site -- up to 5.5 percent
  • Fever -- up to 1.9 percent.
These problems occurred at rates similar to what is seen with just Tripedia alone.
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ActHIB Vaccine Information

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