Children's Tylenol Drug Interactions

Codeine and Acetaminophen (Capital and Codeine, Phenco-Care, Tylagesic, Tylenol No. 3, Tylenol No. 4)
In general, you should avoid giving your child Children's Tylenol if he or she is taking codeine and acetaminophen products, as you may give your child too much acetaminophen (the active ingredient of Children's Tylenol).
 
Isoniazid (Nydrazid)
Taking Children's Tylenol and isoniazid together may increase the risk of liver damage. Talk to your child's healthcare provider before using these medications together.
 
Phenobarbital (Luminal)
Phenobarbital can affect the way your child's body handles Children's Tylenol, making it both less effective and more toxic. Talk to your child's healthcare provider about using Children's Tylenol if your child is taking phenobarbital.
 
Several Cough, Cold, Flu, and Allergy Products
Many of these types of medications contain acetaminophen, the active ingredient of Children's Tylenol. Only use one of these products at a time, so that you do not inadvertently give your child too much acetaminophen.
 
Warfarin (Coumadin, Jantoven)
Taking warfarin with Children's Tylenol may increase the risk of bleeding. However, this risk is much less than for other non-prescription pain relievers (such as aspirin). Talk with your child's healthcare provider about the best ways to treat pain and fevers in a child who is taking warfarin.
 

Final Thoughts on Children's Tylenol Drug Interactions

Not all Children's Tylenol drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions with Children's Tylenol that may apply to you. It is important to watch for acetaminophen in any products, particularly non-prescription products.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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