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Comvax Side Effects

In clinical studies, the most common problems reported with Comvax included drowsiness, fever, and irritability. Serious reactions may also occur. Tell a healthcare provider right away if your child develops a high fever, a seizure, or any signs of an allergic reaction, which are Comvax side effects that require prompt medical care.

An Introduction to Comvax Side Effects

As with all vaccines, side effects are possible with Comvax® (Hib vaccine and hepatitis B vaccine). However, not everyone who receives the vaccine will have problems. In fact, most children tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with this vaccine. Your healthcare provider can discuss a more complete list of Comvax side effects with you.)

Common Side Effects of Comvax

Comvax has been studied thoroughly in clinical trials. In these studies, the side effects that occurred in a group of children given Comvax (which combines two different vaccines) were documented and compared to those that occurred in a similar group of children given the same vaccines separately (at the same time but not in the same injection). This way, it is possible to see what side effects occurred, how often they appeared, and how they compare to the group receiving the vaccines separately.
In these studies, the most common Comvax side effects included:
  • Irritability -- in up to 57 percent of children
  • Drowsiness -- up to 49.5 percent
  • Fever -- up to 14.2 percent
  • Crying -- up to 10.6 percent
  • Loss of appetite -- up to 3.9 percent.
Other common reactions (occurring in 1 to 3 percent of children) included:
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Comvax Vaccine Information

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