Currently, Comvax is unavailable due to problems with the manufacturing process, but is expected to return to the market at an unknown time.
(Click Comvax Uses for more information on what the medication is used for, including possible off-label uses.)
Thimerosal Content and Other Concerns
Comvax does not contain thimerosal (a mercury-containing preservative). Parents who are concerned about exposing their children to thimerosal can be confident that this vaccine has no thimerosal -- not even trace amounts.
Some parents also are concerned about the aluminum content of vaccines. Comvax contains 225 mcg (0.225 mg) of aluminum per dose.
This vaccine is not made from human fetal components or animal components, unlike some vaccines.
Comvax is made by Merck & Co., Inc.
This vaccine contains
hepatitis B surface antigens, which are proteins on the outer surface of the virus that can be recognized by the immune system. Unlike older versions of the hepatitis vaccine, currently available vaccines (including Comvax) are not made using human blood products. Instead, they are made using recombinant DNA technology. This vaccine is not "live," so there is absolutely no chance that a person could get hepatitis B from it.
This vaccine also contains
Hib polysaccharides, which are sugar molecules from the outside coating of the Hib bacteria.
The components of this vaccine "trick" the body into thinking it has been exposed to Hib bacteria and
hepatitis B virus, without the risk of being exposed to the actual bacteria or virus. The body produces antibodies that will help fight infection if future exposure occurs.
When and How to Get Vaccinated
Some general considerations to keep in mind about Comvax include the following:
- This vaccine is typically given as three doses. Ideally, the first dose is given at two months of age, although it can be given to newborns as young as six weeks old.
- Comvax is injected into a muscle (intramuscularly), usually in the thigh.
- Children can be vaccinated if they have a minor illness, such as the common cold. However, the vaccine should be postponed if the child is moderately or severely ill.
There is only one standard recommended dose for this vaccine
(see Comvax Dosage for more information).
Just like any vaccine, Comvax may cause side effects. However, not everyone who receives the vaccine will experience problems. In fact, most children tolerate it well, with only minor side effects, if any.
If side effects do occur, in most cases, they are minor and either require no treatment or can be treated easily by you or your healthcare provider. Serious reactions are less common.
Some of the most common side effects seen with Comvax include but are not limited to:
- Irritability
- Drowsiness
- Fever
- Crying.
(Click Comvax Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
What Should I Tell My Child's Healthcare Provider?
You should talk with your child's healthcare provider before your child receives the Comvax vaccine if your child has:
- An immune-suppressing condition such as HIV or AIDS, diabetes, or cancer
- A bleeding disorder
- Had any sort of a reaction to a vaccine
- A moderate or severe illness
- Any allergies, including to foods, dyes, or preservatives.
Make sure to tell the healthcare provider about all of the medicines your child takes, including prescription and nonprescription medicines, vitamins, and herbal supplements.
How Should Comvax Be Stored?
Comvax should be stored in the refrigerator. The vaccine should never be frozen.
Comvax is available in 0.5-mL single-use vials.
Is There a Generic Version?
