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Daptacel Warnings and Precautions

There are many precautions and warnings to be aware of before your child gets the Daptacel vaccine. For example, if your child has a moderate or severe illness, it is best to postpone the vaccine. Your child should not receive Daptacel at all if he or she has a progressive neurological disorder or has had a serious reaction within seven days after any pertussis-containing vaccine in the past.

What Should I Tell the Healthcare Provider Before My Child Gets Daptacel?

You should talk to a healthcare provider before your child receives Daptacel® (DTaP) if your child has:
  • Had any sort of a reaction to any vaccine in the past
  • A moderate or severe illness
  • A brain or nervous system disorder
  • An immune-suppressing condition such as HIV or AIDS, diabetes, or cancer
  • A bleeding disorder
  • Any allergies, including allergies to foods, dyes, or preservatives.
Make sure to tell the healthcare provider about any medications your child is taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Daptacel Warnings and Precautions

Warnings and precautions to be aware of prior to getting the vaccine include the following:
  • Like all vaccines, Daptacel may not protect all individuals.
  • Daptacel does not contain thimerosal (a mercury-containing preservative) or other preservatives. Parents who are concerned about exposing their children to thimerosal can be confident that this vaccine has no thimerosal (not even trace amounts). Some parents are concerned about aluminum content of vaccines; Daptacel does contain aluminum (0.33 mg per dose).
  • This vaccine is not made from human fetal components or bovine (cow) components, as some vaccines are.
  • Febrile seizures (seizures associated with high fevers in young children) have been associated with vaccines, including Daptacel, probably because vaccines can cause fevers.
If your child has a tendency to get febrile seizures, ask your healthcare provider if you should give an anti-fever medication such as acetaminophen (Tylenol®) or ibuprofen (Advil®, Motrin®). It may be recommended to take an anti-fever medication just before the immunization and for 24 hours afterwards.
  • Your child can receive Daptacel if he or she has a mild illness (such as the common cold). However, it is usually best to postpone the vaccine in the case of a moderate or severe illness.
  • Make sure your healthcare provider knows if you have ever had any serious reactions to any vaccines in the past. It is probably a good idea to ask your parents or other caregivers if you had any problems with your childhood vaccinations.
  • Care must be taken when giving any intramuscular injection (including Daptacel) to individuals with bleeding disorders or who are taking anticoagulant medications ("blood thinners"). In some cases, your child's healthcare provider may decide that the risk of the injection is not worth the benefit.
  • If you have an immune-suppressing condition, Daptacel may not be as effective as usual.
  • The vial stoppers from single-use Daptacel vials are made of natural latex rubber. This could be a concern for individuals with latex allergies.
  • Daptacel is considered a pregnancy Category C medication. This means it is unknown if the vaccine is safe for use during pregnancy. However, this is a childhood vaccine and should not be given to pregnant women.
  • At this time, it is unknown if Daptacel passes through breast milk. However, this is a childhood vaccine and should not be given to breastfeeding women.
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Daptacel Vaccine Information

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