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Symptoms of Fever Blisters

While the majority of people do not develop any fever blister symptoms during their initial infection, about 15 percent develop small, painful blisters around the lips. Other common signs include sore throat, swollen neck glands, and soreness in the mouth or on the lips. Recurrent symptoms are usually less severe and may include pain, itching, tingling, or burning.

When Do Fever Blister Symptoms Start?

When a person is infected with a herpes simplex virus (the virus that causes fever blisters), symptoms do not begin right away. This period between becoming infected and the beginning of symptoms is known as the incubation period. While this period can be anywhere from 1 to 26 days, the average herpes incubation period is 6 to 8 days.

Initial Symptoms of Fever Blisters

In about 85 percent of people, the initial infection with a herpes simplex virus causes no symptoms. However, about 15 percent of people develop many small, sometimes painful, fluid-filled reddish or purple blisters around the lips or corner of the mouth. Over several days, the blisters tend to merge and then collapse. A yellowish crust often forms over the sores, which usually heal without scarring within two weeks.
Besides blisters, other symptoms of fever blister can include:
  • Fever
  • Swollen neck glands
  • Sore throat
  • Soreness in the mouth or on the lips
  • General body aches (malaise).

Recurrent Symptoms

After the initial infection (whether or not symptoms occur), the body is not able to completely get rid of the herpes simplex virus. Instead, the virus remains in a nerve located near the cheekbone. It may stay permanently inactive in this site (in other words, not cause symptoms), or it may occasionally travel down the nerve to the skin surface, causing a recurrence of blisters. Recurring fever blisters usually erupt at the outside edge of the lip or the edge of the nostril, but can also occur on the chin, cheeks, or inside the mouth.
One to three days before the fever blisters return, many people feel pain, itching, tingling, or a burning sensation. This is known as a prodrome.
The symptoms of recurrent attacks are usually less severe than the initial attack. While different for everyone, a fever blister typically lasts 4 to 10 days and occurs three or four times a year, on average.
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Fever Blister Information

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