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Fluocinonide Topical Solution Side Effects

Reported Side Effects

For many medications (particularly newly approved drugs), the prescribing information carefully explains the exact percentage of side effects that were reported in clinical trials. However, the prescribing information for almost all older medications, including fluocinonide topical solution, includes relatively vague information on possible side effects.
 
Based on this limited information, the most common side effects of fluocinonide topical solution may include:
 
  • Burning
  • Irritation
  • Itching
  • Dryness
  • Irritation or infection of hair follicles of the skin (folliculitis)
  • Increased sweating
  • Acne
  • Loss of skin pigment (lightening of the skin)
  • Rash around the mouth
  • Allergic skin rash
  • Whitening and softening of the skin
  • Infections
  • Weakening and thinning of the skin
  • Stretch marks
  • "Prickly heat" sweat rash (miliaria).
 
In general, side effects are more likely to occur if a dressing, such as a bandage, is used to cover the medication. Do not use a dressing unless your healthcare provider specifically recommends that you do so.
 

Long-Term Fluocinonide Topical Solution Side Effects

Using steroids like fluocinonide topical solution over long periods of time can cause a different set of side effects. These reactions are most likely to be seen in people who use this medicine over a large area of the body for a long period of time. Some of the problems seen with long-term use might include:
 
  • Weight gain
  • Bulging eyes
  • Fluid retention
  • Osteoporosis
  • Loss of muscle
  • Fat deposits on the face and back (causing a round face and a fatty hump on the back of the neck)
  • Diabetes
  • Cataracts
  • Stunted growth (in children).
 
Keep in mind that these effects are more common with systemic steroids, which are taken by mouth or injection, and are probably rare with fluocinonide topical solution when used as directed and for a short period of time.
 
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Fluocinonide Topical Solution Information

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