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Fluocinonide Topical Solution Side Effects
Although many people do not have problems while using fluocinonide topical solution, side effects may occur and can include burning, dryness, and itching of the skin. These types of reactions are usually minor and easy to treat. However, there are also some problems that are potentially serious and should be reported to a healthcare provider immediately, including extreme aggression, hallucinations, or difficulty breathing.
Just like any medicine, fluocinonide topical solution (Lidex®) can cause side effects. However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with fluocinonide topical solution. Your healthcare provider can discuss a more complete list with you.)
Some side effects of fluocinonide topical solution are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
- High blood pressure (hypertension)
- High blood sugar levels (hyperglycemia) or diabetes
- Infections
- Ruptured tendons
- Psychotic reactions, such as hallucinations or extreme aggression
- Glaucoma
- Severe fluid retention
- Signs of an allergic reaction, such as:
- An unexplained rash
- Hives
- Itching
- Unexplained swelling
- Difficulty breathing or swallowing.
In general, these serious reactions are extremely unlikely to occur when fluocinonide topical solution is used as directed for a short period of time. Applying too much over too large an area, for extended periods of time may increase the risk for serious steroid side effects.
Written by/reviewed by: Kristi Monson, PharmD
Last reviewed by: Kristi Monson, PharmD



