Precautions and Warnings With Fluticasone Propionate Lotion

Because fluticasone propionate lotion is not suitable for everyone, make sure your healthcare provider is aware of any allergies you have or if you are pregnant or breastfeeding. Other precautions and warnings with fluticasone propionate lotion include complications this steroid might cause when used for long periods, such as Cushing's syndrome or the possibility that the body may stop making its own natural steroids.

What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to using fluticasone propionate lotion (Cutivate Lotion®) if you:
 
  • Are pregnant or thinking of becoming pregnant
  • Are breastfeeding
  • Have any allergies, including to foods, dyes, or preservatives.
 
You should also tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
 

Specific Fluticasone Propionate Lotion Precautions and Warnings

Some warnings and precautions to be aware of before using this medicine include the following:
 
  • Fluticasone propionate lotion contains an inactive ingredient (imidurea) that breaks down into formaldehyde. This should not be a significant concern, except for people who are allergic to formaldehyde.
 
  • This medicine is a steroid and can cause serious side effects, such as Cushing's syndrome or diabetes. Although this is more likely to occur with oral or injectable steroids, it is still possible with topical steroids, including fluticasone propionate lotion. The more you apply and the longer you use the drug, the more likely these problems are to occur. Covering the medicine with a dressing, which is not recommended, may also increase this risk.
 
  • It is not recommended to use fluticasone propionate lotion for more than four weeks at a time. Although the drug is quite effective, it should not be used on a long-term basis.
 
  • If you use this medication for an extended period, it may lead to Cushing's syndrome (a group of symptoms caused by prolonged exposure to steroids). Contact your healthcare provider if you develop signs of this condition, such as:
 
    • A rounded face
    • Unusual body fat distribution (more fat in the trunk, face, and neck, and less fat in the arms and legs)
    • High blood sugar levels.
 
  • Fluticasone propionate lotion can suppress the body's ability to make natural steroids. This typically happens when large doses are used over a long period. In such circumstances, this medication should be stopped gradually to give your body a chance to begin making its own natural steroids again. If this is not feasible, you might need to take an oral steroid for a while, after which you will slowly be weaned off it.
 
  • Like all steroids, fluticasone propionate lotion may slow down the growth rate of children and teenagers. Contact your child's healthcare provider if you are concerned about this. In general, children may be more susceptible to the side effects of steroids. Close monitoring is necessary for any child receiving long-term steroids.
 
  • If you develop a skin infection while using this medication, you will need to be treated with appropriate antibiotics or antifungal medications. If the infection does not clear up, you may need to stop using fluticasone propionate lotion.
 
 
  • This product is a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are currently unknown (see Cutivate Lotion and Pregnancy).
 
  • It is unknown if this medicine passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to using the lotion (see Cutivate Lotion and Breastfeeding).
 
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Fluticasone Propionate Lotion Information

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