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Hiberix Drug Interactions
If Hiberix is combined with anticoagulant medicines or immunosuppressants, drug interactions may occur. Anticoagulants may include warfarin or heparin; immunosuppressants include corticosteroids, chemotherapy, tacrolimus, and certain monoclonal antibodies. Drug interactions with Hiberix may lead to decreased effectiveness of the vaccine or other problems.
An Overview of Hiberix Interactions
An Overview of Hiberix Interactions
Hiberix® (Hib vaccine) can potentially interact with a few medications. Some of the medicines that may lead to interactions with Hiberix include:
- Anticoagulant medications, such as warfarin (Coumadin®, Jantoven®) or heparin
- Immunosuppressants, such as:
- Azathioprine (Imuran®)
- Certain monoclonal antibodies, including:
- Abatacept (Orencia®)
- Adalimumab (Humira®)
- Alemtuzumab (Campath®)
- Basiliximab (Simulect®)
- Daclizumab (Zenapax®)
- Efalizumab (Raptiva®)
- Infliximab (Remicade®)
- Chemotherapy (as well as radiation treatment)
- Corticosteroids, such as:
- Betamethasone (Celestone®)
- Cortisone
- Dexamethasone (Decadron®)
- Fludrocortisone (Florinef®)
- Hydrocortisone (Cortef®)
- Methylprednisolone (Depo-Medrol®, Medrol®)
- Prednisolone (Pediapred®)
- Prednisone
- Triamcinolone (Kenalog®)
- Cyclophosphamide (Cytoxan®)
- Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
- Etanercept (Enbrel®)
- Methotrexate (Rheumatrex®)
- Mycophenolate (CellCept®)
- Sirolimus (Rapamune®)
- Tacrolimus (Prograf®).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD