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Drug Interactions With Imipramine Hydrochloride

Tramadol
Combining imipramine hydrochloride with tramadol may increase the risk of serotonin syndrome. Check with your healthcare provider before taking these medications together.
 
Tricyclic Antidepressants
If imipramine is combined with other tricyclic antidepressants, this can increase your risk of side effects. Your healthcare provider may need to adjust your dose of these medications to prevent this from occurring.
 
Triptans
Combining imipramine hydrochloride with a triptan may increase the risk of serotonin syndrome. Check with your healthcare provider before taking these medications together.
 
Tryptophan
Combining imipramine hydrochloride with tryptophan may increase the risk of serotonin syndrome. Check with your healthcare provider before taking these medications together.
 

Final Thoughts on Drug Interactions With Imipramine Hydrochloride

It is possible that not all drug interactions with imipramine hydrochloride were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific interactions that may apply to you.
 
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Imipramine HCl

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