Imipramine Hydrochloride (Cont.)

Alternatives to Imipramine Hydrochloride for Depression

Depression, even in its most severe form, is highly treatable. As with many illnesses, getting treatment early is more effective and reduces the chance of recurrence.
 
The most common forms of treatment for depression are medication (antidepressants) and psychotherapy ("talk therapy"). In cases of severe depression, healthcare providers may recommend electroconvulsive therapy (ECT). Some people may also try complementary or alternative treatments for depression (see Natural Remedies for Depression).
 
Imipramine hydrochloride is quite effective at treating depression. It is also generally well tolerated. However, side effects can occur, or the medicine may not work as well as needed. In these cases, your healthcare provider may recommend an alternative to imipramine. Examples of substitute depression medications include:
 
  • Other tricyclic antidepressants
  • Selective serotonin reuptake inhibitors (SSRIs)
  • Serotonin-norepinephrine reuptake inhibitors (SNRIs)
  • Norepinephrine and dopamine reuptake inhibitors (NDRIs)
  • Monoamine oxidase inhibitors (MAOIs).
     
(Click Imipramine Alternatives for more information. Click Dealing With Depression to learn about other ways of managing depression.)
 
(Imipramine Hydrochloride Continued: Page 6)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;