What Is Imipramine Hydrochloride Used For?

What is imipramine hydrochloride used for? The medication can help treat depression in adults and bedwetting in children. It is effective in significantly improving symptoms of depression. And although it is not a cure for bedwetting, the drug can help relax the bladder muscles to prevent bedwetting at night. Imipramine hydrochloride is used for "off-label" reasons as well, such as the treatment of bulimia, anxiety disorder, and fibromyalgia.

 

What Is Imipramine Hydrochloride Used For? -- An Overview

Imipramine hydrochloride (Tofranil®) is a prescription medicine licensed to treat the following conditions:
 
  • Depression (also known as major depression or clinical depression) in adults
  • Bedwetting in children.
     

Imipramine Hydrochloride Uses for Depression

Depression is more than just "feeling sad." Common symptoms of depression include:
 
  • Changes in sleep (sleeping too much or not enough)
  • Eating too much or too little (and weight gain or weight loss)
  • Having little interest in things that you used to enjoy
  • Physical pain
  • Feeling hopeless or worthless
  • Suicidal thoughts.
     
Imipramine has been proven in large clinical trials to help adults with depression. However, keep in mind that many antidepressants (including imipramine) take several weeks to begin working. Sometimes, other people will notice an improvement in your symptoms before you do. Often, the physical symptoms of depression (such as pain or changes in sleep) will improve first -- sometimes very quickly. It usually takes a few weeks before significant changes in mood occur, so it is important to give imipramine a chance to work before becoming discouraged.
 
Counseling and therapy (see Psychotherapy for Depression) are often used along with antidepressant medications to treat depression. Ask your healthcare provider if either of these would be good options for you (see Depression Treatment).
 
(What Is Imipramine Hydrochloride Used For? Continued: Page 2)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;