Infanrix ® ( DTaP) is a childhood vaccine. It is a combined vaccine that provides protection against the following diseases:
(Click Infanrix Uses for more information on what the medication is used for, including possible off-label uses.)
Thimerosal Content and Other Concerns
Infanrix does not contain thimerosal (a mercury-containing preservative) or other preservatives. Parents who are concerned about exposing their children to this substance can be confident that this vaccine has no thimerosal -- not even trace amounts. Some parents are concerned about the aluminum content of vaccines; Infanrix contains aluminum (0.625 mg or less per dose).
This vaccine is not made from human fetal components, as some vaccines are. While it is made using bovine (cow) materials, the materials come from countries that do not have (or are not at high risk for) bovine spongiform encephalopathy, also known as mad cow disease.
Infanrix is made by GlaxoSmithKline Biologicals.
This vaccine contains several different components, including tetanus toxoids, diphtheria toxoids, and pertussis antigens. None of the components of this vaccine are "live," which means that the vaccine cannot cause diphtheria, tetanus, or pertussis.
It is also important to note that the pertussis component of this vaccine is acellular (not made up of whole pertussis cells) and is much safer than the previous whole-cell pertussis vaccine that was used in the past.
Simply stated, the components of this vaccine work by "tricking" the body into thinking it has been exposed to these different infections. The body produces antibodies that will help fight the infections if future exposure occurs.
When and How to Take Infanrix
Some general considerations for those taking the medicine include the following:
- This vaccine is typically given as a five-dose series. The first dose is usually given at two months of age, and the fifth dose is given between four and six years of age.
- Infanrix is injected into a muscle (intramuscularly), usually in the thigh for infants. In older children, the upper arm can be used.
- Children can be vaccinated if they have a minor illness, such as the common cold. However, the vaccine should be postponed if the child is moderately or severely ill.
Dosing Information
There is only one standard recommended dosage for this vaccine, although there is some flexibility in the vaccination schedule (see Infanrix Dosage for more information).
Just like any vaccine, Infanrix may cause side effects. However, not everyone who receives the vaccine will experience problems. In fact, most children tolerate it well, with only minor reactions, if any. If side effects do occur, in most cases, they are minor and either require no treatment or can be treated easily by you or your healthcare provider. Serious side effects are less common.
Some of the most common side effects include but are not limited to:
- Fussiness or irritability
- Drowsiness
- Loss of appetite
- Injection site reactions such as pain, swelling, or redness
- Fever.
(Click Infanrix Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
What Should I Tell My Child's Healthcare Provider?
You should talk to a healthcare provider before your child receives the Infanrix vaccine if your child has:
- An immune-suppressing condition such as HIV or AIDS, diabetes, or cancer
- A bleeding disorder
- Had any sort of a reaction to a vaccine in the past
- A moderate or severe illness
- A brain or nervous system disorder
- Any allergies, including allergies to foods, dyes, or preservatives.
Make sure to tell the healthcare provider about all medicines your child is taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
How Should Infanrix Be Stored?
Infanrix should be stored in the refrigerator. It should never be frozen.
The vaccine is available in 0.5-mL single-use vials or disposable prefilled syringes (without needles). The prefilled syringes contain latex, while the vials do not.
Is There a Generic Version?
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