Infant Tylenol Drug Interactions

Codeine and Acetaminophen (Capital and Codeine, Phenco-Care, Tylagesic, Tylenol No. 3, Tylenol No. 4)
In general, you should avoid giving your child infant Tylenol if he or she is taking codeine and acetaminophen products, as you may give your child too much acetaminophen (the active ingredient of infant Tylenol).
 
Isoniazid (Nydrazid)
Taking infant Tylenol drops and isoniazid together may increase the risk of liver damage. Talk to your child's healthcare provider before using these medications together.
 
Many Cough, Cold, Flu, and Allergy Products
Many of these types of medications contain acetaminophen, the active ingredient of infant Tylenol. Only use one of these products at a time, so that you do not inadvertently give your child too much acetaminophen.
 
Phenobarbital (Luminal)
Phenobarbital can affect the way your child's body handles infant Tylenol, making it both less effective and more toxic. Talk to your child's healthcare provider about using infant Tylenol if your child is taking phenobarbital.
 
Warfarin (Coumadin, Jantoven)
Taking warfarin with infant Tylenol may increase the risk of bleeding. However, this risk is much less than for other non-prescription pain relievers (such as aspirin). Talk with your child's healthcare provider about the best ways to treat pain and fevers in a child that takes warfarin.
 

Final Thoughts on Infant Tylenol Drug Interactions

Not all infant Tylenol drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions with infant Tylenol that may apply to your child. It is important to watch for acetaminophen in any product, particularly non-prescription products.
 
(For a more complete list of medications that interact with Tylenol, including medications that are not likely to be taken by children, see Tylenol Drug Interactions.)
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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