Infant Tylenol Drug Interactions

If phenobarbital, isoniazid, or non-prescription cold and cough medications are combined with infant Tylenol, drug interactions may potentially occur. Some drugs may affect the way the body handles Tylenol, while others can increase the risk of liver damage. To help prevent infant Tylenol interactions, make sure to tell your child's healthcare provider about all other medicines your child is taking.

 

Infant Tylenol Drug Interactions: An Overview

Concentrated Tylenol® Infants' Drops (infant acetaminophen) can potentially interact with other medications. However, many of these medications are not usually used by young children. Some of the children's medicines that may lead to infant Tylenol drug interactions include:
 
  • Carbamazepine (Carbatrol®, Epitol™, Equetro®, Tegretol®)
  • Codeine and acetaminophen (Capital® and Codeine, Phenco-Care™, Tylagesic™, Tylenol No. 3, Tylenol No. 4)
  • Isoniazid (Nydrazid®)
  • Many non-prescription cough, cold, flu, and allergy products
  • Phenobarbital (Luminal®)
  • Warfarin (Coumadin®, Jantoven®).

 

(The official name of this product is "Concentrated Tylenol Infants' Drops." However, this article uses the name interchangeably with "infant Tylenol," since this is how the drug is commonly referred to.)

 

Infant Tylenol Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when infant Tylenol is combined with any of the drugs listed above.
 
Carbamazepine (Carbatrol, Epitol, Equetro, Tegretol)
Carbamazepine can affect the way the body handles infant Tylenol, making both drugs less effective and more toxic. Talk to your child's healthcare provider about using infant Tylenol drops in children who take carbamazepine.
(Infant Tylenol Drug Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;