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IPOL Side Effects

Irritability, tiredness, and tenderness at the injection site are the most common reactions that have been reported with IPOL. Side effects of the vaccine are often mild and, in most cases, do not require medical attention. However, certain side effects are potentially serious and should be reported to your healthcare provider immediately, including high fever or unusual behavioral changes.

An Introduction to IPOL Side Effects

As with all vaccines, side effects are possible with IPOL® (inactivated polio vaccine). However, not everyone who receives the vaccine will have problems. In fact, most children tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or can be treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with IPOL. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of IPOL

IPOL has been studied thoroughly in clinical trials. In these studies, IPOL was usually given at the same time as the DTP vaccine (an older version of the diphtheria, tetanus, and pertussis vaccine). Therefore, it is difficult to determine exactly how much each vaccine contributed to the different side effects.
In these studies, the most common side effects of IPOL (given along with DTP) included:
  • Irritability -- in up to 64.5 percent of people
  • Tiredness -- up to 60.7 percent
  • Tenderness at the injection site -- up to 29.4 percent
  • Loss of appetite -- up to 16.6 percent
  • Vomiting -- up to 2.8 percent
  • Persistent crying -- up to 1.4 percent
  • Redness at the injection site -- up to 1 percent.
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IPOL Vaccine Information

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