Drug Interactions With IPV

Immunosuppressants and anticoagulants may react negatively with IPV. Caution should be used when giving intramuscular injections to people taking anticoagulants. Also, the vaccine may not be as effective for people taking immunosuppressants. To help limit these drug interactions with IPV, tell your healthcare provider about all medications you are taking and any medical conditions you have before getting vaccinated.

An Overview of Interactions With IPV

• Anticoagulant medications, such as warfarin (Coumadin^®, Jantoven^®) or heparin
• Immunosuppressants, such as:

• Azathioprine (Imuran^®)
• Certain biologic medications, such as:

• Abatacept (Orencia^®)
• Adalimumab (Humira^®)
• Alefacept (Amevive^®)
• Alemtuzumab (Campath^®)
• Anakinra (Kineret™)
• Basiliximab (Simulect^®)
• Canakinumab (Ilaris^®)
• Certolizumab pegol (Cimzia^®)
• Daclizumab (Zenapax^®)
• Eculizumab (Soliris^®)
• Efalizumab (Raptiva^®)
• Etanercept (Enbrel^®)
• Gemtuzumab ozogamicin (Mylotarg^®)
• Glatiramer (Copaxone^®)
• Golimumab (Simponi™)
• Infliximab (Remicade^®)
• Ibritumomab (Zevalin^®)
• Muromonab-CD3 (Orthoclone OKT^®)
• Natalizumab (Tysabri^®)
• Ofatumumab (Arzerra™)
• Rilonacept (Arcalyst™)
• Rituximab (Rituxan^®)
• Tositumomab (Bexxar^®)
• Ustekinumab (Stelara™)

• Chemotherapy (as well as radiation treatment)
• Corticosteroids, such as:

• Betamethasone (Celestone^®)
• Cortisone
• Dexamethasone (Decadron^®)
• Fludrocortisone (Florinef^®)
• Hydrocortisone (Cortef^®)
• Methylprednisolone (Depo-Medrol^®, Medrol^®)
• Prednisolone (Pediapred^®)
• Prednisone
• Triamcinolone (Kenalog^®)

• Cyclophosphamide (Cytoxan^®)
• Cyclosporine (Gengraf^®, Neoral^®, Sandimmune^®) 
• Methotrexate (Rheumatrex^®)
• Mycophenolate (CellCept^®)
• Sirolimus (Rapamune^®)
• Tacrolimus (Prograf^®).