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IPV Dosage

Depending on the particular brand of IPV, dosage recommendations will vary. The standard polio vaccine series consists of four doses (for young children) or three doses (for adults or adolescents). With two particular brands, a booster shot is needed, as these products do not fully complete the recommended vaccination schedule.

Dosing for IPV: An Introduction

The dosage for IPV (inactivated polio vaccine) that your healthcare provider recommends will vary, depending on the following factors:
  • The particular IPV vaccine
  • The vaccination history of the individual
  • The age of the individual.

Preferred IPV Schedule

IPV is available by itself (IPOL®) or in combination with other routine vaccines (Pediarix®, Pentacel®, Kinrix®). For IPOL, the standard dose is 0.5 mL injected intramuscularly (into a muscle) or just under the skin (subcutaneously). For infants, the thigh is usually chosen, while the upper arm is generally preferred for toddlers or older children. The ideal vaccination schedule for IPOL is as follows:
  • First dose -- 2 months old
  • Second dose -- 4 months old
  • Third dose -- 6 to 18 months old
  • Fourth dose -- 4 to 6 years old.
The first dosage can be given as early as six weeks of age, and there should be at least four weeks in between the others.
The recommended schedules for the various IPV-containing combination vaccines are outlined in the following table.
Brand Name
Vaccine Components
Dosing Schedule

DTaP, IPV, and hepatitis B vaccine

2, 4, and 6 months of age


DTaP, IPV, and Hib vaccine

2, 4, 6, and 15 to 18 months of age


DTaP and IPV

4 to 6 years of age

Both Pediarix and Pentacel should be followed by an IPV booster (either IPOL or Kinrix) at four to six years of age, since Pediarix and Pentacel do not fully complete the recommended IPV schedule. Notice that giving Pentacel plus a booster at four to six years of age results in one extra IPV vaccination (five instead of four). This is acceptable and is not thought to be a problem.
7 Easy Tips for Starting Solids

IPV Information

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