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Lupron Side Effects

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Some side effects of Lupron are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
- Blood in the urine or difficulty urinating
- Persistent or extreme bone pain
- Puberty signs after two months of treatment in children, including vaginal bleeding or spotting in girls
- Chest pain (angina)
- Tingling, pricking, or numbing sensations of the skin
- Weakness in the legs
- Signs of a blood clot, such as:
- Severe pain
- Swelling
- Weakness
- Numbness of an arm or leg
- Signs of a blood clot in the lung, such as:
- Shortness of breath
- Sudden chest pain
- Coughing up blood
- Signs of anemia, such as:
- Fatigue
- Pale skin
- Dizziness
- Shortness of breath
- Black, tarry, or bloody stools
- Vomit that looks like coffee grounds or has bright red blood in it
- Extreme shortness of breath or coughing
- Mood changes, such as:
- Depression
- Nervousness
- Anxiety
- Mood swings
- Feelings of a rapid or forcefully beating heart (palpitations)
- Reactions at the injection site, such as:
- Severe redness
- Pain
- Pus
- Bleeding
- Bone fracture
- Seizure
- Changes in blood sugar levels or signs of diabetes, such as:
- Frequent urination
- Increased thirst
- Blurred vision
- Fatigue
- Weight loss
- Signs of pituitary apoplexy, which is death of an area of tissue in the pituitary gland, such as:
- A sudden, severe headache
- Paralysis of the eye muscles
- Blurred vision
- Nausea and vomiting
- Low blood pressure
- Confusion
- Signs of an allergic reaction, such as:
- Hives
- Itching
- Unexplained swelling of the mouth or throat
- Wheezing
- Difficulty breathing or swallowing.
Written by/reviewed by: Susan Lakey, PharmD, MPH
Last reviewed by: Kristi Monson, PharmD



