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Lupron Uses

How Does This Medicine Work?

Lupron is similar to gonadotropin-releasing hormone (GnRH), a hormone found naturally in the body. GnRH controls the release of two other hormones from the pituitary gland (a tiny gland located beneath the brain): luteinizing hormone (LH) and follicle stimulating hormone (FSH). These two hormones stimulate production of sex hormones (testosterone and estrogen) in the ovaries and testicles.
 
Normally, when GnRH is released by the body, LH and FSH levels increase and more sex hormones are produced. Because Lupron is similar to GnRH, this series of events occurs when Lupron is first given, causing an initial rise in sex hormone levels. However, after two to four weeks of Lupron use, the body stops releasing LH and FSH, and testosterone and estrogen are no longer produced.
 
In most cases, testosterone stimulates the growth of prostate cancer cells. By reducing testosterone levels, Lupron slows down or prevents the growth of the testosterone-dependent cancer cells. This can help reduce the symptoms of cancer.
 
Lupron works to treat precocious puberty by blocking the production of sex hormones (testosterone in boys and estrogen in girls), which temporarily stops puberty.
 

Can Children Use It?

Lupron is approved to treat central precocious puberty in children. Talk with your child's healthcare provider about the particular benefits and risks of using this medicine in children.
 

Is It Safe for Older Adults?

Lupron has been studied in older adults and is approved for use in older adults for the treatment of prostate cancer. This medication is as safe and effective in older adults as it is in younger age groups.
 

Off-Label Uses for Lupron

On occasion, your healthcare provider may recommend this medicine for something other than the uses discussed in this article. This is known as an "off-label" use. Possible off-label uses of Lupron include:
 
  • Managing endometriosis
  • Relieving symptoms of breast and ovarian cancer
  • Treating uterine fibroids.
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Lupron Drug Information

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