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Adacel Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Adacel is combined with any of the drugs listed above.
If you are taking an immunosuppressant, you may not receive the full benefit of Adacel for protection from tetanus, diphtheria, and pertussis (whooping cough). With some vaccines (especially live vaccines), people taking immunosuppressants may be at a higher risk of actually developing the infection (usually a mild form) from the vaccine. However, because Adacel is not a live vaccine, this is not a problem.
Other Vaccines
Studies indicate that giving Adacel at the same time as the influenza vaccine ("flu shot") might slightly reduce the effectiveness of Adacel. Giving Adacel with the hepatitis B vaccine does not seem to interfere with either of the vaccines.
Adacel has not been studied in combination with any other vaccines. If other vaccines are given at the same time, different syringes and different injection sites must be used. Adacel should not be combined with any other vaccines in the same syringe.
Tetanus Immune Globulin
If Adacel and tetanus immune globulin must be given at the same time, they should be given with different syringes and needles at different parts of the body.

Final Thoughts

It is possible that not all interactions with Adacel were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions that may apply to you.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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