Kids Home > Amoxicillin/Clavulanate Potassium ES

What If I My Child Takes an Overdose?

People who take too much of this medication may have overdose symptoms that could include:
 
  • Abdominal pain (or stomach pain)
  • Vomiting
  • Diarrhea
  • Rash
  • Hyperactivity
  • Drowsiness
  • Kidney damage.
     
If your child happens to overdose on this medication, seek immediate medical attention (see Augmentin ES Overdose).
 

What Should I Do If My Child Misses a Dose?

If your child misses a scheduled dosage, have him or her take the missed dose as soon as possible. However, if it is almost time for the next dose, simply skip the missed dose and continue with the regular schedule. Do not give your child a double dose. Because this medication is an antibiotic, it is important to try not to miss any doses.
 

How Does Amoxicillin/Clavulanate Potassium ES Work?

Amoxicillin/clavulanate potassium ES contains two different medications, amoxicillin and clavulanate potassium (also known as clavulanic acid, or simply clavulanate). Amoxicillin belongs to a group of medications known as aminopenicillins, which is part of a larger group of medications known as beta-lactam antibiotics (named after the ring-like "lactam" structure of these antibiotics).
 
Amoxicillin works by stopping bacteria from making cell walls, which eventually causes the bacteria to die. However, many bacteria have developed a resistance to amoxicillin (and similar antibiotics) by producing enzymes called beta-lactamases. Beta-lactamases (produced by bacteria) break the beta-lactam ring, making amoxicillin (and similar antibiotics) ineffective.
 
The other component of amoxicillin/clavulanate potassium ES (clavulanate) is known as a beta-lactamase inhibitor. Clavulanate stops the bacterial enzymes from breaking down the amoxicillin molecule. Clavulanate itself has no significant antibacterial activity; it merely helps to prevent amoxicillin from being broken down by bacteria that would otherwise be resistant to amoxicillin. Essentially, clavulanate "augments" the activity of amoxicillin (hence the name Augmentin).
 
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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