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There are potential drug interactions with the Boostrix vaccine. For example, taking it with other medications, such as immunosuppressants, tetanus immune globulin, or other vaccines, can reduce the effectiveness of Boostrix. To avoid problems, it is important to talk to your healthcare provider about any other medications you are taking.

An Overview of Boostrix Drug Interactions

Boostrix® (Tdap vaccine) can potentially interact with a few medications or other vaccines. Some of the medicines or vaccines that may lead to drug interactions with Boostrix include:
  • Immunosuppressants, such as:
    • Chemotherapy (as well as radiation treatment)
    • Corticosteroids, such as:
      • Betamethasone (Celestone®)
      • Cortisone
      • Dexamethasone (Decadron®)
      • Fludrocortisone (Florinef®)
      • Hydrocortisone (Cortef®)
      • Methylprednisolone (Depo-Medrol®, Medrol®)
      • Prednisolone (Pediapred®)
      • Prednisone
      • Triamcinolone (Kenalog®)
  • Other vaccines
  • Tetanus immune globulin.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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