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Is Imipramine Hydrochloride Used for Children and Teens?

Imipramine is not recommended for treating depression in people under 18 years old, as it has not been thoroughly studied as a depression medication in these age groups. For bedwetting, imipramine is approved for children as young as six years old. Talk to your healthcare provider about using imipramine in children or teenagers.

Is Imipramine Hydrochloride Used for Off-Label Reasons?

On occasion, your healthcare provider may recommend imipramine for treating something other than conditions listed in this article. This is called an "off-label" use. At this time, there are several off-label imipramine uses, such as:
  • Chronic pain: Imipramine works best for chronic pain that is nerve-related, such as nerve pain due to shingles (including postherpetic neuralgia).
  • Anxiety disorder: Many antidepressants (including imipramine) are used to treat anxiety disorders.
  • Incontinence: The drug is sometimes used to treat problems with bladder control in adults.
  • Attention deficit hyperactivity disorder (ADHD): Imipramine can be used to treat ADHD, especially if other medications have not been effective or cause side effects.
  • Fibromyalgia: The drug has been used to treat pain and other symptoms of fibromyalgia.
  • Migraine headaches: Imipramine can be used on a daily basis to prevent migraine headaches. However, it is not effective for treating a migraine headache once it starts.
  • Bulimia: The medication has been found to improve symptoms of bulimia, including binge eating and vomiting.
  • Smoking cessation: Imipramine is sometimes used to help people quit smoking.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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