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Side Effects of Menactra

Just like any vaccine, Menactra may cause side effects. However, not everyone who receives the vaccine will experience problems. In fact, most people tolerate it well, with only minor side effects, if any. If side effects do occur, in most cases, they are minor and either require no treatment or can be treated easily by you or your healthcare provider. Serious reactions are less common.
Some of the most common side effects seen with Menactra include but are not limited to:
  • Injection site reactions, such as pain, redness, or swelling
  • Headache
  • Fatigue
  • A general ill feeling (malaise).
(Click Menactra Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)

Drug Interactions

Menactra can potentially interact with a few medications (see Menactra Drug Interactions).

What Should I Tell My Healthcare Provider?

Before you receive the Menactra vaccine, tell your healthcare provider if you have:
  • Guillain-Barré syndrome
  • An immune-suppressing condition, such as HIV or AIDS, diabetes, or cancer
  • Had any sort of a reaction to a vaccine before
  • A moderate or severe illness
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Make sure to tell the healthcare provider about all of the medications you take, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Menactra Warnings and Precautions to learn more, including information on who should not get vaccinated.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
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