Natroba

If you have head lice, your doctor may prescribe a medication called Natroba. This product comes in the form of a liquid that is applied to the hair and scalp for ten minutes for one or two treatments. It may take less than one bottle or up to a full bottle per application. The most common side effect is skin irritation at the application site.

What Is Natroba?

Natroba® (spinosad) is a prescription medication approved for treating head lice. It can be used to treat children as young as four years of age.
 
(Click Natroba Uses for more information on this topic, including possible off-label uses.)
 

Who Makes Natroba?

Natroba is made by ParaPRO LLC.
 

How Does It Work?

The active ingredient (spinosad) causes lice to become hyperactive, after which they become paralyzed and die. Spinosad is derived from the fermentation of a certain type of soil bacteria. It is also used as an insecticide in lawn and garden products.
 

How Effective Is Natroba?

Two different clinical studies have compared Natroba to permethrin cream (Nix®) for treating head lice. In both studies, Natroba was much more effective. In one study, 84.6 percent of people given Natroba were free of lice 14 days after treatment, compared to only 44.9 percent of those given Nix. The other study showed similar results.
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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