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Menactra Drug Interactions
Medications such as anticoagulants and immunosuppressants have been known to cause drug interactions with Menactra. For example, people taking immunosuppressants such as cortisone, prednisone, or Enbrel may not receive Menactra's full benefits, as the immune system may have trouble responding to the vaccine. To reduce your risk of interactions, tell your healthcare provider about any medications you are taking.
Menactra® (meningococcal vaccine) could potentially interact with a few medications. Some of the medicines that may lead to Menactra drug interactions include:
- Anticoagulants (commonly known as "blood thinners"), such as warfarin (Coumadin®, Jantoven®) or heparin
- Immunosuppressants, such as:
- Azathioprine (Imuran®)
- Certain biologic medications, such as:
- Abatacept (Orencia®)
- Adalimumab (Humira®)
- Alefacept (Amevive®)
- Alemtuzumab (Campath®)
- Anakinra (Kineret™)
- Basiliximab (Simulect®)
- Canakinumab (Ilaris®)
- Certolizumab pegol (Cimzia®)
- Daclizumab (Zenapax®)
- Eculizumab (Soliris®)
- Efalizumab (Raptiva®)
- Etanercept (Enbrel®)
- Gemtuzumab ozogamicin (Mylotarg®)
- Glatiramer (Copaxone®)
- Golimumab (Simponi™)
- Infliximab (Remicade®)
- Ibritumomab (Zevalin®)
- Muromonab-CD3 (Orthoclone OKT®)
- Natalizumab (Tysabri®)
- Ofatumumab (Arzerra™)
- Rilonacept (Arcalyst™)
- Rituximab (Rituxan®)
- Tositumomab (Bexxar®)
- Ustekinumab (Stelara™)
- Chemotherapy (as well as radiation treatment)
- Corticosteroids, such as:
- Betamethasone (Celestone®)
- Cortisone
- Dexamethasone (Decadron®)
- Fludrocortisone (Florinef®)
- Hydrocortisone (Cortef®)
- Methylprednisolone (Depo-Medrol®, Medrol®)
- Prednisolone (Pediapred®)
- Prednisone
- Triamcinolone (Kenalog®)
- Cyclophosphamide (Cytoxan®)
- Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
- Methotrexate (Rheumatrex®)
- Mycophenolate (CellCept®)
- Sirolimus (Rapamune®)
- Tacrolimus (Prograf®).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD



