Menactra Side Effects

In clinical studies, the most common side effect of Menactra was pain at the injection site (occurring in 59.2 percent of people). Other common reactions included fatigue, joint pain, and headache. In most cases, side effects are mild and can be treated easily. However, if you experience serious problems, such as hives, difficulty breathing, or throat swelling, contact your healthcare provider right away.

An Introduction to Menactra Side Effects

As with all vaccines, side effects are possible with Menactra® (meningococcal vaccine). However, not everyone who receives the vaccine will have problems. In fact, most people tolerate it quite well. If adverse reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
 
(This article covers many, but not all, of the possible side effects with Menactra. Your healthcare provider can discuss a more complete list with you.)
 

Common Side Effects of Menactra

Menactra has been studied thoroughly in clinical trials. In these studies, Menactra was compared to an older version of the meningococcal vaccine (Menomune®). In the clinical trials, any possible side effects were carefully documented.
 
Based on the information from these studies, the most common Menactra side effects included:
 
  • Pain at the injection site -- in up to 59.2 percent of individuals
  • Irritability (in young children) -- up to 56.8 percent
  • Headache -- up to 41.4 percent
  • Fatigue -- up to 34.7 percent
  • Abnormal crying (in young children) -- up to 33.3 percent
  • Drowsiness (in young children) -- up to 33.3 percent
  • Appetite loss (in young children) -- up to 30.2 percent
  • Redness at the injection site -- up to 30.2 percent
  • Malaise -- up to 23.6 percent.
  •   
Other common side effects (occurring in 1 to 20 percent of people) included but were not limited to:
 
  • Swelling or a lump at the injection site
  • Vomiting
  • Joint pain
  • Diarrhea
  • Loss of appetite
  • Fever
  • Vomiting
  • A rash
  • Chills.
     
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
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