Monospot Test (Cont.)

Other Tests to Diagnosis Mono

If the doctor suspects mono based on your symptoms and physical exam, he or she can order other tests besides the monospot test.
 
Additional tests that can help your doctor make a mononucleosis diagnosis include:
 
  • A complete blood count (CBC) to see if your blood platelet count is lower than normal and if your lymphocytes (lymph cells) are abnormal
  • A chemistry panel to see if your liver enzymes are abnormal.
 
Also, if your throat is sore, having a throat culture is usually a good idea for several reasons. First, the symptoms of mono and strep infection -- including that caused by strep-A (a particularly serious form of strep bacteria) -- are very similar. Second, strep throat or other throat infections can develop at any time during or shortly after mononucleosis. In any case, it's important that throat infections be diagnosed as soon as possible and treated with antibiotics that can kill the organism responsible for the infection.
 
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Written by/reviewed by: Arthur Schoenstadt, MD
Last reviewed by: Arthur Schoenstadt, MD