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Pediarix Drug Interactions
A number of medications may interact with Pediarix. For example, problems may occur if you get vaccinated while you are also taking anticoagulant medicines or immunosuppressants (such as chemotherapy, cyclosporine, or certain monoclonal antibodies). Drug interactions could decrease the effectiveness of the vaccine or lead to other problems.
An Overview of Pediarix Interactions
An Overview of Pediarix Interactions
Pediarix® (DTaP, hepatitis B vaccine, and inactivated polio vaccine) can potentially interact with a few medications. Some of the medicines that may lead to interactions with Pediarix include:
- Anticoagulant medications, such as warfarin (Coumadin®, Jantoven®) or heparin
- Immunosuppressants, such as:
- Azathioprine (Imuran®)
- Certain monoclonal antibodies, including:
- Abatacept (Orencia®)
- Adalimumab (Humira®)
- Alemtuzumab (Campath®)
- Basiliximab (Simulect®)
- Daclizumab (Zenapax®)
- Efalizumab (Raptiva®)
- Infliximab (Remicade®)
- Chemotherapy (as well as radiation treatment)
- Corticosteroids, such as:
- Betamethasone (Celestone®)
- Cortisone
- Dexamethasone (Decadron®)
- Fludrocortisone (Florinef®)
- Hydrocortisone (Cortef®)
- Methylprednisolone (Depo-Medrol®, Medrol®)
- Prednisolone (Pediapred®)
- Prednisone
- Triamcinolone (Kenalog®)
- Cyclophosphamide (Cytoxan®)
- Cyclosporine (Gengraf®, Neoral®, Sandimmune®)
- Etanercept (Enbrel®)
- Methotrexate (Rheumatrex®)
- Mycophenolate (CellCept®)
- Sirolimus (Rapamune®)
- Tacrolimus (Prograf®).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD