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Pediarix Drug Interactions

A number of medications may interact with Pediarix. For example, problems may occur if you get vaccinated while you are also taking anticoagulant medicines or immunosuppressants (such as chemotherapy, cyclosporine, or certain monoclonal antibodies). Drug interactions could decrease the effectiveness of the vaccine or lead to other problems.

An Overview of Pediarix Interactions

Pediarix® (DTaP, hepatitis B vaccine, and inactivated polio vaccine) can potentially interact with a few medications. Some of the medicines that may lead to interactions with Pediarix include:




    • Chemotherapy (as well as radiation treatment)
    • Corticosteroids, such as:


      • Betamethasone (Celestone®)
      • Cortisone
      • Dexamethasone (Decadron®)
      • Fludrocortisone (Florinef®)
      • Hydrocortisone (Cortef®)
      • Methylprednisolone (Depo-Medrol®, Medrol®)
      • Prednisolone (Pediapred®)
      • Prednisone
      • Triamcinolone (Kenalog®)


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Pediarix Vaccine Information

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