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PedvaxHIB Drug Interactions

Azathioprine, Coumadin, cortisone, and methotrexate are among the products that can cause drug interactions with PedvaxHIB. When these medications are combined with PedvaxHIB, they can cause the vaccine to lose its effectiveness. Therefore, it is important to tell the healthcare provider administering the injection about all medicines your child is currently taking, including vitamins and supplements.

An Overview of Interactions With PedvaxHIB

PedvaxHIB® (Hib vaccine) can potentially interact with a few different types of medications. Some of the medicines that may lead to PedvaxHIB drug interactions include:
  • Anticoagulant medications (commonly known as "blood thinners"), such as warfarin (Coumadin®, Jantoven®) or heparin
  • Immunosuppressants (medications that suppress the immune system), such as:
    • Chemotherapy (as well as radiation treatment)
    • Corticosteroids, such as:
      • Betamethasone (Celestone®)
      • Cortisone
      • Dexamethasone (Decadron®)
      • Fludrocortisone (Florinef®)
      • Hydrocortisone (Cortef®)
      • Methylprednisolone (Depo-Medrol®, Medrol®)
      • Prednisolone (Pediapred®)
      • Prednisone
      • Triamcinolone (Kenalog®)
A Dose of Reassurance for Parents of Picky Eaters

PedvaxHIB Vaccine Information

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