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PedvaxHIB Warnings and Precautions

Healthcare providers may not recommend PedvaxHIB for children who have had an adverse reaction to vaccines before. Precautions and warnings with PedvaxHIB also apply to children with bleeding disorders, conditions that suppress the immune system, and certain allergies. Therefore, it is important to provide your healthcare provider with your child's complete medical history when considering this vaccine.

What Should I Tell My Child's Healthcare Provider?

Before your child receives PedvaxHIB® (Hib vaccine), tell the healthcare provider if your child has:
  • An immune-suppressing condition, such as HIV or AIDS, diabetes, or cancer
  • Had any sort of a reaction to a vaccine
  • A moderate or severe illness
  • A bleeding disorder
  • Any allergies, including to foods, dyes, or preservatives.
Make sure to tell the healthcare provider about any medications your child is taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.

Specific PedvaxHIB Warnings and Precautions

Safety precautions and warnings to be aware of prior to your child receiving the PedvaxHIB vaccine include the following:
  • Sometimes, children get a Hib infection the week after getting PedvaxHIB. This is not due to the vaccine; in such cases, the child had already been exposed to the bacteria before getting the vaccine, and it takes a while for the vaccine to start working.
  • Make sure your healthcare provider knows if your child has ever had any serious reactions to any vaccines. In some cases, this and other vaccines may not be recommended.
  • If your child has an immune-suppressing condition, PedvaxHIB may not be as effective as usual for protection against Haemophilus influenzae type b (Hib).
  • PedvaxHIB does not contain thimerosal (a mercury-containing preservative). Parents who are concerned about exposing their children to this substance can be confident that this vaccine has no thimerosal -- not even trace amounts. Some parents also are concerned about the aluminum content of vaccines; PedvaxHIB contains 0.225 mg of aluminum per dose.
  • This vaccine is not made from human fetal components or animal components, unlike some vaccines.


  • The vial for this vaccine contains dry natural latex rubber, which may cause reactions in people with latex allergies. 


  • Care must be taken when giving any intramuscular injection, including PedvaxHIB, to individuals with bleeding disorders or who are taking anticoagulant medications ("blood thinners"). In some cases, your child's healthcare provider may decide that the risk of the injection is not worth the benefit.
  • Your child can receive PedvaxHIB if he or she has a mild illness, such as the common cold. However, it is usually best to postpone the vaccine in the case of a moderate or severe illness.
  • PedvaxHIB is considered a pregnancy Category C medication. This means it is unknown if it is safe for use during pregnancy. However, this is a childhood vaccine and should not be given to pregnant women.
  • At this time, it is unknown if PedvaxHIB passes through breast milk. However, this is a childhood vaccine and should not be given to breastfeeding women.
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PedvaxHIB Vaccine Information

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