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Pimecrolimus Side Effects

Common Side Effects

Pimecrolimus has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people using pimecrolimus were carefully documented and compared to those that occurred in a group of people using a different medication or a placebo (a similar product that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the other groups.
In these studies, the most commonly reported pimecrolimus side effects included:
  • Upper respiratory tract infections, such as the common cold -- in up to 26.5 percent of people
  • Burning or warmth at the application site -- up to 25.9 percent
  • Headaches -- up to 25.4 percent
  • Coughing -- up to 15.8 percent
  • Other skin reactions at the application site, such as irritation, redness, and itching -- up to 14.6 percent
  • Influenza -- up to 13.2 percent
  • Fever -- up to 12.5 percent
  • Sore throat -- up to 8.1 percent
  • Stomach flu -- up to 7.4 percent
  • Diarrhea -- up to 7.7 percent
  • Viral infections -- up to 6.6 percent
  • Vomiting -- up to 6.6 percent.
Other common reactions, occurring in 1.1 to 6.4 percent of people, included but were not limited to:
  • Skin infections, such as:
  • Swelling of the tonsils
  • Ear infections or earaches
  • Abdominal (stomach) pain
  • Stuffy or runny nose
  • Nausea
  • Worsening asthma
  • Constipation
  • Toothache
  • Nosebleeds
  • Eye infections or irritation, including pink eye
  • Swollen or infected hair follicles
  • Acne
  • Back pain
  • General infections
  • Shortness of breath or wheezing
  • Painful menstrual cramps
  • Joint pain
  • Accidental injuries, including skin cuts or wounds
  • Hives.
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Pimecrolimus Drug Information

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