Pneumococcal Conjugate Vaccine Dosage

As with many vaccines, there is only one standard dosage of the pneumococcal conjugate vaccine (0.5 mL). The vaccine is injected into a muscle, usually either in the thigh or upper arm. Although this dosing is the same for everyone, the vaccination schedule will vary from person to person, depending on their age at the first dose.

Pneumococcal Conjugate Vaccine Dosage: An Introduction

There is only one standard dosage for the pneumococcal conjugate vaccine (Prevnar 13®), although the vaccine schedule may vary, depending on the age of the individual at the first dosing.
 

Preferred Schedule

The preferred vaccine schedule is exactly the same for either vaccine formulation (the old Prevnar or the new Prevnar 13). The standard pneumococcal conjugate vaccine dosage is 0.5 mL injected intramuscularly (into a muscle). For infants, the thigh is usually chosen, while the upper arm is generally preferred for toddlers or older children. The ideal vaccination schedule for the pneumococcal conjugate vaccine is as follows:
 
  • First dose -- 2 months old
  • Second dose -- 4 months old
  • Third dose -- 6 months old
  • Fourth dose -- 12 to 15 months old.
     
The first dosage can be given as early as six weeks of age, and there should be at least four to eight weeks in between the doses. The fourth dosage should be given at least two months after the third dosage.
 
Prevnar 13 can (and should) be used to complete the series for any child who started but has not yet finished the series with the older Prevnar vaccine. The old Prevnar vaccine is no longer being made.
 
In addition, all children under the age of five who have previously completed the older Prevnar series should receive one dose of Prevnar 13 in order to benefit from the extra protection this new vaccine provides.
 
Also, it is recommended that children between 6 and 18 years of age who are at an increased risk for invasive pneumococcal disease because of sickle cell disease, HIV infection (or other immunocompromising condition), cochlear implant, or cerebrospinal fluid leaks should receive one dose of Prevnar 13, regardless of previous vaccination with Prevnar or Pneumovax. This is an off-label use for the vaccine, though, since it is approved (in children) for use only up until the sixth birthday.
 
Prevnar 13 is also approved for use in adults age 50 and older. For this age group, the dosage is 0.5 mL injected intramuscularly for a single dose.
  
 
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Pneumococcal Conjugate Vaccine Information

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