ProQuad Drug Interactions

Immunosuppressants, aspirin, and immune globulins are among the drugs that can cause negative interactions with ProQuad. Some of these interactions can decrease the effectiveness of the vaccine or increase the risk for potentially dangerous problems. Before receiving the ProQuad injection, make sure your healthcare provider knows if you are taking any other prescription or nonprescription medicines, vitamins, or supplements.

An Overview of Interactions With ProQuad

ProQuad^® (MMRV) can potentially react with a number of other medications. Some of the products that may lead to ProQuad drug interactions include but are not limited to:

Immune globulins or blood products (such as a blood transfusion)
Immunosuppressants, such as:
- Azathioprine (Imuran^®)
- Certain biologic medications, such as:

Abatacept (Orencia^®)
Adalimumab (Humira^®)
Alefacept (Amevive^®)
Alemtuzumab (Campath^®)
Anakinra (Kineret™)
Basiliximab (Simulect^®)
Canakinumab (Ilaris^®)
Certolizumab pegol (Cimzia^®)
Daclizumab (Zenapax^®)
Denosumab (Prolia™)
Eculizumab (Soliris^®)
Efalizumab (Raptiva^®)
Etanercept (Enbrel^®)
Glatiramer (Copaxone^®)
Golimumab (Simponi™)
Infliximab (Remicade^®)
Ibritumomab (Zevalin^®)
Muromonab-CD3 (Orthoclone OKT^®)
Natalizumab (Tysabri^®)
Ofatumumab (Arzerra™)
Rilonacept (Arcalyst™)
Rituximab (Rituxan^®)
Tositumomab (Bexxar^®)
Ustekinumab (Stelara™)

Corticosteroids, such as:

Betamethasone (Celestone^®)
Cortisone
Dexamethasone (Decadron^®)
Fludrocortisone (Florinef^®)
Hydrocortisone (Cortef^®)
Methylprednisolone (Depo-Medrol^®, Medrol^®)
Prednisolone (Pediapred^®)
Prednisone
Triamcinolone (Kenalog^®)

Cyclophosphamide (Cytoxan^®)
Cyclosporine (Gengraf^®, Neoral^®, Sandimmune^®)
Etanercept (Enbrel^®)
Methotrexate (Rheumatrex^®)
Mycophenolate (CellCept^®)
Sirolimus (Rapamune^®)
Tacrolimus (Prograf^®)

Salicylates, such as:
- Aspirin (Ecotrin^®, Bayer^®, Anacin^®)
- Choline magnesium trisalicylate (Trilisate^®), diflunisal (Dolobid^®)
- Salsalate (Salflex^®, Disalcid^®, Amigesic^®)