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When and How to Take ProQuad

Some general considerations to keep in mind with this vaccine include the following:
  • This vaccine can be given in place of the individual MMR and varicella vaccines (both of which are usually given as two doses each). Typically, the first dose would be given at age 12 to 15 months, and the second dose would be given at 4 to 6 years of age.
  • Because of the increased risk for fever and febrile seizures (seizures caused by fevers) in children 12 to 23 months of age, it is generally preferred to give the first MMR and varicella vaccines separately instead of using ProQuad. Giving them separately has a lower risk for such problems. Therefore, this vaccine will typically be used primarily for the second dose only in children 4 to 6 years of age.
  • As with other live vaccines, ProQuad is injected subcutaneously (just under the skin), preferably on the upper arm.
  • Children can be vaccinated if they have a minor illness, such as the common cold. However, the vaccine should be postponed if the individual is moderately or severely ill.

Dosing Information

There is only one standard recommended dosage for this vaccine, regardless of age or weight (see ProQuad Dosage for more information).

Side Effects of ProQuad

Just like any vaccine, ProQuad can cause side effects. However, not everyone who receives the vaccine will have problems. Most children tolerate it quite well, with only minor side effects, if any.
Some of the most common side effects of ProQuad include but are not limited to:
  • Injection site reactions (pain, tenderness, swelling, or redness at the injection site)
  • Fever
  • Irritability.
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
(Click ProQuad Vaccine Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
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ProQuad Vaccine Information

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