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Sklice and Pregnancy

When given to pregnant animals, the active ingredient in Sklice (ivermectin lotion) appeared to increase the risk for serious birth defects and fetal death. Due to these risks, Sklice is classified as a pregnancy Category C medication. This means that this drug should only be given to a pregnant woman when the benefits to the mother outweigh the risks to the unborn child.

Can Pregnant Women Use Sklice?

Sklice® (ivermectin lotion) is a prescription head lice medication. Based on the results of animal studies, this medication might not be safe for use during pregnancy.

What Is Pregnancy Category C?

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Sklice is classified as a pregnancy Category C medication.
Pregnancy Category C is given to medicines that have not been adequately studied in pregnant humans but do appear to cause fetal harm in animal studies. In addition, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
When given to animals at high doses, ivermectin (the active ingredient in Sklice) caused serious birth defects and fetal death. However, these problems only occurred at doses that were high enough to be toxic to the mothers as well.
In a few studies involving oral use of ivermectin in humans as part of community-wide efforts to treat parasitic infections in developing countries, some pregnant women were inadvertently exposed to the drug. Comparing these babies to those not exposed to the medication, ivermectin does not appear to increase the risk of any problems.
It is important to note that pregnancy Category C medicines, including Sklice, may be given to a pregnant woman if her healthcare provider believes that the benefits to the woman outweigh any possible risks to the unborn child.
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