The recommended dosage of Synagis for the prevention of serious respiratory syncytial virus (RSV) infections will depend on the child's weight. Because children grow quickly, the amount will have to be recalculated before each dose. This medication comes as an injection that is given into a muscle once a month during RSV season, which typically occurs from November to April.
The dose of Synagis® (palivizumab) your healthcare provider recommends will vary, depending on your weight. As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
The usual dose of Synagis for the prevention of serious respiratory syncytial virus (RSV) infections is 15 mg per kg body weight (about 6.8 mg per lb) once a month. The first dose is usually given before the RSV season begins, and monthly doses continue throughout the season. The RSV season typically occurs from November to April, but may start earlier or end later in some areas.
Because Synagis is usually given to young children (who grow rapidly), it is important to weigh the child before every dose. The amount that was right for last time might not be enough the next month.
Children who have cardiopulmonary bypass (a technique whereby a machine takes over the function of the heart and lungs, normally during open heart surgery) should receive a Synagis dosage as soon as possible after their procedure, even if it has been less than a month since the last dose. Thereafter, the regular monthly dosing schedule can continue.
Some considerations to keep in mind during treatment with Synagis include the following:
- This medication is given as an intramuscular (IM) injection (an injection into a muscle) once a month during the RSV season. The injection is usually administered in the thigh muscle.
- The injection is normally given by a healthcare provider in a healthcare setting, such as a doctor's office or clinic. You may be taught how to give this medicine at home. If so, make sure you fully understand how to give the injections before doing so.
- The Synagis vial should be inspected before use. This medication should not be used if it contains particles or is discolored.
- Synagis comes in single-use vials. The vial should be thrown away after each dose, even if there is medicine remaining.
- If you are unsure about anything related to your dose or Synagis dosing in general, please talk to your healthcare provider or pharmacist.